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Figure 5 | Journal of Hematology & Oncology

Figure 5

From: Inosine Triphosphate Pyrophosphohydrolase (ITPA) polymorphic sequence variants in adult hematological malignancy patients and possible association with mitochondrial DNA defects

Figure 5

Incidence of N-calls following sPROFILER analysis of the entire mtDNA genome. This illustrates the total distribution of continuous stretches of N-calls in mtDNA (rCRS section) in both sets of AHM patients, those carrying the ITPA 94A mutation and those homozygous for the ITPA 94C wildtype allele. Continuous stretches of >5 N-calls were re-analysed by conventional sequencing.

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