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Figure 1 | Journal of Hematology & Oncology

Figure 1

From: B-Raf and the inhibitors: from bench to bedside

Figure 1

B-Raf protein and signaling pathways. The B-Raf protein and its related signaling pathway are shown along with potential targets for treatment. A) The PI3K/AKT/mTOR and Ras/Raf/MAPK signaling pathways are shown along with potential targets. B) The structural domains of the B-Raf isoforms are shown. The position of the V600E mutation is indicated (arrow).

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