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Table 2 Univariate and multivariate analysis of various potential prognostic factors in gastric cancer patients

From: L1cam promotes tumor progression and metastasis and is an independent unfavorable prognostic factor in gastric cancer

Factors

Univariate analysis

 

Multivariate analysis

Case NO.

HRb(95% CIc)

P

HRb(95% CIc)

P

Age (<60/≥60)

87/69

0.94(0.61-1.44)

0.785

-

-

Gender (male/female)

106/50

1.17(0.74-1.84)

0.511

-

-

Differentiation (well, moderate/poor)

77/79

0.79(0.46-1.74)

0.381

-

-

Therapeutic strategyd(Sur/Sur + Chemo)

86/70

1.21(0.79-1.86)

0.377

-

-

Tumor size (≥5 cm/<5 cm)

105/51

2.27(1.54-3.37)

0.001a

1.73(0.99-3.03)

0.055

Lymph node invasion (present/absent)

111/45

1.55(1.25-1.92)

0.012a

1.05(0.73-1.53)

0.780

TNM stage (III-IV/I-II)

108/48

1.95(1.48-2.55)

0.001a

1.36(0.81-2.31)

0.249

L1cam expression (high/low)

71/85

2.73(1.76-4.25)

<0.001a

1.94(1.27-4.31)

0.022a

  1. aP < 0.05.
  2. bHR, hazard ratio.
  3. cCI, confidence interval.
  4. dSur, Surgery only, Sur + Chemo: Surgery plus adjuvant Chemotherapy.