Figure 3From: Erythropoietin is a JAK2 and ERK1/2 effector that can promote renal tumor cell proliferation under hypoxic conditionsThe effects of erythropoietin on cell cycle. Cells, which were starved for 18Â hrs in normoxic or hypoxic conditions then treated with or without rhEPO for additional 10Â hrs in normoxic or hypoxic condition, were analyzed. Specifically, the percentage of population in G0/G1, S, and G2/M phase of the cell cycle were analyzed by flow cytometry after propidium iodide staining of cellular DNA. Arrows indicate the major changes in EPO-treated cells compared to untreated cells. Data are representatives from three independent experiments.Back to article page