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Figure 2 | Journal of Hematology & Oncology

Figure 2

From: Stem cell factor SALL4, a potential prognostic marker for myelodysplastic syndromes

Figure 2

SALL4 and Bmi-1 shared a similar expression pattern in MDS: both were increased in high-grade morphology and high IPSS score cases. (A) SALL4 and Bmi-1 expression in subtypes of MDS according to WHO classification. (B) SALL4 and Bmi-1 expression in different IPSS risk groups. (C) Representative SALL4 and Bmi-1 protein expression analyzed by western blot. The protein expression of SALL4 in RAEB-1/RAEB-2 was higher than that of healthy control. Bmi-1 protein expression followed a similar trend. THP-1 cell line was used as a positive control. (D) Semi-quantitatively analysis demonstrated that this trend was statistically significant for SALL4 but not for Bmi-1. * P-value<0.05, **p-value<0.01, ***p-value<0.001, ns: no significance. The lines indicate mean value of each group.

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