Figure 2

G-CSF/anti-G-CSF mAb complexes enhance immunity against bacterial infection. (A) B6 mice (n = 5/group) were treated i.p. on days 1, 3, and 5 with G-CSF/anti-G-CSF mAb complexes (1.5 μg G-CSF plus 7.5 μg anti-G-CSF mAb), G-CSF alone (1.5 μg G-CSF), or vehicle alone. On day 7, mice were injected i.v. with 1x10⁵ colony-forming units (CFU) of Listeria monocytogenes (LM-OVA). (B) On day 10, spleens were harvested and the number of CFU was determined. The triangles indicate individual mice and the bar indicates the average per group. *P-values ≤ 0.05 were generated by Wilcoxon Rank-Sum test.