Table 4 A comparison of conventional cytogenetic (CG) and fluorescence in situ hybridization (FISH) results
| Â | FISH positve | FISH negative | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
Probe | No. of patients | BMIhisto+/ | BMIhisto+/ | BMIhisto-/ | BMIhisto-/ | No. of patients | BMIhisto+/ | BMIhisto+/ | BMIhisto-/ | BMIhisto-/ |
| Â | Â | CGwhole+ | CGwhole- | CGwhole+ | CGwhole- | Â | CGlocus+ | CGlocus- | CGlocus+ | CGlocus- |
14q32/IGH | 37/235 (15.7) | 20 (54.1) | 11 (29.7) | 3 (8.1) | 3 (8.1) | 198/235 (84.3) | 6 (3.0) | 54 (27.3) | 0 (0.0) | 138 (69.7) |
9p21/p16 | 17/178 (9.6) | 14 (82.4) | 3 (17.6) | 0 (0) | 0 (0) | 161/178 (90.4) | 3 (1.9) | 50 (31.1) | 0 (0) | 108 (67.1) |
3q27/BCL6 | 19/95 (20.0) | 14 (73.7) | 5 (26.3) | 0 (0) | 0 (0) | 76/95 (80.0) | 2 (2.6) | 28 (36.8) | 0 (0) | 46 (60.5) |
8q24/MYC | 7/50 (14.0) | 5 (71.4) | 2 (28.6) | 0 (0) | 0 (0) | 43/50 (86.0) | 3 (7.0) | 12 (27.9) | 1 (2.3) | 27 (67.8) |
1p32/1q25 | 9/49 (18.4) | 9 (100) | 0 (0) | 0 (0) | 0 (0) | 40/49 (81.6) | 1 (2.5) | 21 (52.5) | 0 (0) | 18 (45.0) |
17p13/TP53 | 3/34 (8.8) | 1 (33.3) | 2 (66.7) | 0 (0) | 0 (0) | 31/34 (91.2) | 0 (0) | 8 (25.8) | 0 (0) | 23 (74.2) |
18q23/BCL2 | 3/29 (10.3) | 0 (0) | 2 (66.7) | 1 (33.3) | 0 (0) | 26/29 (89.7) | 2 (7.7) | 7 (26.9) | 0 (0) | 17 (65.4) |