Figure 1
TGF-β1-induced EMT results in drug resistance phenotype. Dose–response curves shows that A549M cells exhibit increased cell viability, after treatment with erlotinib (A) and cisplatin (B), compared to A549 cells. Cells were treated with indicated concentrations of erlotinib/cisplatin for 72 hours and then subjected to MTT assay. The IC50 and IC90 values for different conditions are provided in the table within the individual figures. ND: IC90 could not be determined. *p<0.05.