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Figure 5 | Journal of Hematology & Oncology

Figure 5

From: Enhancing bone marrow regeneration by SALL4 protein

Figure 5

TAT-SALL4B treatment increases the short-term engraftment of mouse or human cells in transplantation. 400,000 c-kit positive bone marrow cells of CD45.1 B6/SJL mice were injected to lethally irradiated CD45.2 C57BL/6 mice, TAT-SALL4B injection augmented the total bone marrow (a) and donor CD45.1 cell numbers (b) in the recipient mice (n = 3). Similar results were observed in transplantation of human CB CD34+ cells into NOD/SCID mice. The total bone marrow cell number (c) and human CD45+ cells (d) in NOD/SCID mice were increased by TAT-SALL4B protein treatment (n = 4).

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