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Table 1 Characteristics of the 45 AML patients at diagnosis

From: FISH+CD34+CD38- cells detected in newly diagnosed acute myeloid leukemia patients can predict the clinical outcome

 

All patients

FISH + CD34 + CD38-

FISH + CD34 + CD38-

P value

N = 45

<1%

≥1%

N = 20

N = 25

Gender

    

  Male(%)

25(55.6)

10(50)

15(60)

0.557

  Female(%)

20(44.4)

10(50)

10(40)

 

Age, Median(range)

42(14–71)

36(19–71)

45(14–66)

0.5600

WBC, Median(range)

14.5(0.63-143)

12.4(0.63-125.24)

14.9(1.7-143)

0.9091

PLT, Median(range)

42(4–191)

28(4–191)

48(16–157)

0.198

BM blast%

58(18–96)

52.5(20–94.5)

62(18–96)

0.265

FAB subtype

   

0.694

  M1

5

2

3

 

  M2

18

10

8

 

  M4

12

5

7

 

  M5

9

3

6

 

  M6

1

0

1

 

Cytogenetics risk

   

0.894

  Favorable

24

10

14

 

  Intermediate

12

6

6

 

  Poor

9

4

5

 

FLT3 mutations (%)

5(11.1)

2(10)

3(12)

1

Allo-HSCT(%)

14(31.1)

6(30)

8(32)

1

  1. Patients were stratified into favorable (cases with t(8;21), or inv(16), excluding complex cytogenetic), poor (cases with complex cytogenetic changes three or more unrelated abnormalities, t(6;9) or 11q23 abnormalities [excluding t(9;11)]), and intermediate (cases with t(9;11), trisomy 8, 7q-, 9q-, or trisomy 21) risk groups.