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Table 2 The treatment outcome according to LIC Level

From: FISH+CD34+CD38- cells detected in newly diagnosed acute myeloid leukemia patients can predict the clinical outcome

Characteristics

Low LIC load

High LIC load

P value

N = 20

N = 25

Failure of induction therapy

2(10%)

4(16%)

0.678

Overall CR

18(90%)

21(84%)

0.678

Overall relapse

2/18(11.1)

10/21(47.6)

0.018

Treatment-related mortality

2/18(11.1)

5/21(23.8)

0.418

2-year OS

0.7257[0.4082, 0.8916]

0.1675[0.0323, 0.3947]

0.000

2-year EFS

0.6723[0.3262, 0.8687]

0.1633[0.0328, 0.3825]

0.003

2-year CIR

56.7% ± 5.1%

18.0% ± 1.5%

0.021