SNP | Genotype | Controls N (%) | Cases N (%) | OR (95% CI) | p-Values |
---|---|---|---|---|---|
rs13240966 | SLC4A2 | 235 | 173 | ||
GG | 72 (30.64) | 22(12.72) | 1.0 (Ref) | ||
CC | 64 (27.23) | 95 (57.91) | 4.86 (2.74-8.62) | < 0.0001 | |
CG | 99 (42.13) | 56 (32.37) | 1.85 (1.04-3.30) | 0.04 | |
CC + CG | 163 (69.36) | 151 (87.28) | 3.03 (1.79-5.13) | < 0.0001 | |
rs2235074 | ABCB1 | 261 | 188 | ||
GG | 232 (88.55) | 129 (68.62) | 1.0 (Ref) | ||
AA | 1 (0.38) | 0 (0.00) | NA | ||
AG | 28 (10.69) | 59 (31.38) | 3.79 (2.30-6.24) | < 0.0001 | |
AA + AG | 29 (11.07) | 59 (31.38) | 3.66 (2.23-6.00) | < 0.0001 | |
rs20580 | LIG1 | 264 | 191 | ||
CC | 167 (63.26) | 84 (43.98) | 1.0 (Ref) | ||
AA | 20 (7.58) | 33 (17.28) | 3.28 (1.77-6.06) | < 0.0001 | |
AC | 77 (29.17) | 74(38.74) | 1.91 (1.26-2.89) | 0.002 | |
AA + AC | 97 (36.74) | 110 (57.59) | 2.25 (1.54-3.29) | < 0.0001 | |
rs574664 | ROS1 | 262 | 189 | ||
TT | 191 (72.90) | 95 (50.26) | 1.0 (Ref) | ||
AA | 4 (1.53) | 4 (2.12) | 2.01 (0.49-8.22) | 0.32 | |
TA | 67 (25.57) | 90 (47.62) | 2.70 (1.81-4.03) | < 0.0001 | |
AA + TA | 71 (27.10) | 94 (49.74) | 2.66 (1.79-3.95) | < 0.0001 | |
rs732417 | STK6 | 257 | 188 | ||
GG | 203 (78.99) | 113 (60.11) | 1.0 (Ref) | ||
CC | 0 (0.00) | 2 (1.06) | NA | ||
CG | 54 (21.01) | 73 (38.83) | 2.43 (1.60-3.70) | < 0.0001 | |
CC + CG | 54 (21.01) | 75 (39.89) | 2.50 (1.61-3.88) | < 0.0001 | |
rs1042838 | PGR | 253 | 189 | ||
GG | 174 (68.77) | 86 (45.50) | 1.0 (Ref) | ||
TT | 2 (0.79) | 3 (1.59) | 3.04 (0.40-26.49) | 0.34 | |
TG | 77 (30.43) | 100 (52.91) | 2.63 (1.74-3.97) | < 0.0001 | |
TT + TG | 79 (31.23) | 103 (54.50) | 2.64 (1.75-3.98) | < 0.0001 | |
rs8177426 | GPX3 | 260 | 171 | ||
GG | 155 (59.62) | 82 (47.95) | 1.0 (Ref) | ||
AA | 14 (5.38) | 33(19.30) | 4.46 (2.16-9.32) | < 0.0001 | |
AG | 91 (35.00) | 56 (32.75) | 1.16 (0.74-1.82) | 0.51 | |
AA + AG | 105 (40.38) | 92 (53.80) | 1.66 (1.10-2.47) | 0.01 | |
rs11226 | RAD52 | 234 | 171 | ||
CC | (61.11) | 83 (48.54) | 1.0 (Ref) | ||
TT | 17 (7.26) | 32 (18.71) | 3.24 (1.62-6.53) | 0.0002 | |
TC | 74 (31.62) | 56 (32.75) | 1.30 (0.82-2.07) | 0.26 | |
TT + TC | 91 (38.88) | 90 (52.63) | 1.70 (1.15-2.54) | 0.01 | |
rs3797896 | MSH3 | 262 | 191 | ||
CC | 232 (88.21) | 186 (97.38) | 1.0 (Ref) | ||
GG | 3 (1.14) | 0 (0.00) | NA | ||
GC | 27 (10.27) | 5 (2.62) | 0.23 (0.09-0.61) | 0.001 | |
GG + GC | 30 (11.40) | 5 (2.62) | 0.21 (0.08-0.55) | 0.001 |