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Figure 1 | Journal of Hematology & Oncology

Figure 1

From: Targeting MET kinase with the small-molecule inhibitor amuvatinib induces cytotoxicity in primary myeloma cells and cell lines

Figure 1

Expression levels of HGF mRNA, but not MET , in CD138+ cells increase progressively from healthy individuals to myeloma patients. Publically available expression array data was Robust Multichip Average processed and plotted as boxplots of relative (A) MET and (B) HGF mRNA log expression values in healthy donors (normal), and in patients with monoclonal gammopathy of undetermined significance (MGUS), smoldering multiple myeloma (SMM), newly-diagnosed multiple myeloma (MM-N), or relapsed/refractory disease (MM-R). Boxplots show 25th and 75th percentiles and the bold lines as medians. Whiskers show the range of values within the interquantile range from the box, and circles are outliers. Numbers at the bottom of each graph indicate the number of individuals in each category.

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