hIL6, HHV8 and CRP dynamic. Changes in the levels of human interleukin-6 (hIL6), human herpesvirus 8 (HHV8) DNA and serum C-reactive protein (CRP) in Cases 1 and 2 following the initiation of tocilizumab therapy. ● hIL6, △CRP and ■ HHV8 in the serum. ↓ The arrows indicate the time of relapse. The gray boxes indicate the frequency of tocilizumab infusion.