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Figure 5 | Journal of Hematology & Oncology

Figure 5

From: Cysteine- rich secretory protein 3 (CRISP3), ERG and PTEN define a molecular subtype of prostate cancer with implication to patients’ prognosis

Figure 5

Cross-talk between CRISP3 and ERG . 12 genes are implicated in both CRISP3 and ERG samples (A). The 12 genes are connected to p53, CTNNB1, AKT1 and other cell proliferation genes (B). A heatmap showing the prognostic value of combining the status of ERG, PTEN and CRISP3 in samples with GS6 or 3 + 4 in the Swedish data. Hierarchical clustering showed that the three genes define distinct subgroups of patients with GS6 or 3 + 4 (C). The cluster that is enriched with high ERG, CRISP3 and low PTEN showed poorest survival.

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Journal of Hematology & Oncology

ISSN: 1756-8722

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