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Table 3 Top deregulated genes in high CRISP3 expression, ERG positive samples and the pathways they are involved in

From: Cysteine- rich secretory protein 3 (CRISP3), ERG and PTEN define a molecular subtype of prostate cancer with implication to patients’ prognosis

Pathway

Top genes in the 84 set

mTORC mediated signaling

EIF4B

Unwinding of DNA

GINS2

Steroid hormone biosynthesis

HSD17B3

Peptide chain elongation

RPL4, RPL5, RPS3, RPL17

Protein translation and ribosomes

EIF4B, RPL4, RPL5, RPS3, RPL17

Deadenylation of mRNA

EIF4B

Signaling by BMP

BMPR1B