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Table 4 Results of CRISP3 expression in correlation with clinico-pathological parameters from comparatives studies

From: Cysteine- rich secretory protein 3 (CRISP3), ERG and PTEN define a molecular subtype of prostate cancer with implication to patients’ prognosis

Study

Correlation of CRISP 3 expression with clinico-pathological parameters

 
 

Gleason score

Pathological stage

Surgical margins

Outcome

Ribeiro et al. [13]

No

No †

Not Tested

N/A

Grupp et al. [14]

Yes

Yes

Yes

Univariate

Dahlman et al. [10]

No?

No?

No?

Trends*

Hoogland et al. [11]

No

No

No

N/A

Bjartell et al. [12]

No

No

No

Yes

Al-Bashir et al.

No

No

No

Noμ

  1. *There was a trend that patients with high CRISP3 expression had higher risk of biochemical recurrence.
  2. Adding CRISP3 expression to current parameters does not provide any added significance to the prediction.
  3. †Using non-parametric tests on the qRT-PCR data from the validation series.
  4. μBased on protein expression. However, mRNA CRISP3 levels were prognostic based on the validation within Taylor and Swedish cohorts.