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Figure 4 | Journal of Hematology & Oncology

Figure 4

From: Cardiac hypertrophy associated with myeloproliferative neoplasms in JAK2V617F transgenic mice

Figure 4

Masson’s Trichrome stain reveals collagen fibrosis in hearts from JAK2V617F transgenic mice. Representative trichrome stains of heart sections from 40–45 week-old control (A and C) and JAK2V617F transgenic (B and D) mice are shown (magnification, ×40). Note the extensive interstitial (B) and perivascular (D) fibrosis represented by the blue stains. Data in the bar graphs represent quantitative measurements of interstitial (E) and perivascular (F) trichrome staining intensity of at least 5 randomly selected areas from each of 10 control and 10 JAK2V617F transgenic mice. Error bars denote SD (n ≥50). P < 0.001.

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