Figure 3From: Arsenic trioxide induces differentiation of CD133+ hepatocellular carcinoma cells and prolongs posthepatectomy survival by targeting GLI1 expression in a mouse modelAs 2 O 3 inhibited self-renewal and decreased the tumorigenic capacity of CD133+CSCs. (A) Pretreatment of CD133+ Huh7-wt and CD133+ Hep3B-wt cells with 4 μM As2O3 for 5 days inhibited CSC sphere formation. (B) As2O3 also decreased the tumorigenicity of CD133+ cells.Back to article page