Figure 3

xCT inhibition reduces intracellular GSH levels from KSHV-infected PEL cells. (A-B) BCP-1 (A) and BCBL-1 (B) cells were incubated with either MSG or SASP at the indicated concentrations for 24 h, then intracellular glutathione (GSH) was quantified using a commercial kit as described in Methods, and normalized to GSH levels for the vehicle-incubated cells. Error bars represent the S.E.M. for 3 independent experiments. * = p < 0.05; ** = p < 0.01.