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Table 3 Survival of the DS-ALL patients treated according to the ALL-1992/2000 protocols in relation to clinical and genetic features

From: Clinical and genetic features of pediatric acute lymphoblastic leukemia in Down syndrome in the Nordic countries

Features 5-year EFS (SE) P valuea 5-year OS (SE) P valuea
Gender     
 Female 0.619 (0.080) 0.46 0.693 (0.078) 0.50
 Male 0.534 (0.080)   0.621 (0.081)  
Age (years)     
 0-4 0.479 (0.106) 0.88 0.632 (0.091) 0.77
 ≥5 0.558 (0.076)   0.668 (0.073)  
WBC count (×10 9 /l)     
 0-9 0.574 (0.086) 0.78 0.752 (0.076) 0.36
 ≥10 0.574 (0.077)   0.644 (0.074)  
 0-49 0.610 (0.061) 0.026 0.747 (0.055) 0.003
 ≥50 0.364 (0.145)   0.364 (0.145)  
Karyotype     
 Abnormal 0.558 (0.076) 0.86 0.668 (0.073) 0.92
 Normal 0.468 (0.116)   0.661 (0.107)  
  1. DS-ALL, Down syndrome-related acute lymphoblastic leukemia; EFS, event-free survival; OS, overall survival; SE, standard error; WBC, white blood cell.
  2. aSignificant P values in bold type.