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Table 4 Significant difference ( P = 0.005)ain types of event in DS-ALL and non-DS-ALL patients treated according to the ALL-1992/2000 protocols

From: Clinical and genetic features of pediatric acute lymphoblastic leukemia in Down syndrome in the Nordic countries

Events

DS-ALL (% of events)

non-DS-ALL (% of events)

Relapse

23 (66)

507 (80)

Induction failure

9b (26)

47 (7.4)

DCR1

3 (8.6)

48 (7.6)

SMN

0 (0)

32 (5.0)

  1. DS-ALL, Down syndrome-related acute lymphoblastic leukemia; DCR1, death in complete remission 1; SMN, second malignant neoplasm.
  2. aMann-Whitney U test.
  3. bSix of the 9 patients with induction failure died due to toxicity.