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Figure 7 | Journal of Hematology & Oncology

Figure 7

From: Synergistic effects of combined platelet-activating factor receptor and epidermal growth factor receptor targeting in ovarian cancer cells

Figure 7

Effects of the combined PAFR and EGFR targeting on ovarian cancer xenografts. Athymic nude mice were injected subcutaneously into the flank with CAOV-3 cells. (A) Representative photographs of tumors extracted from mice treated with or without WEB2086 (5 mg/kg, i.p., every three days for 2 weeks) and AG1478 (10 mg/kg, i.p., every three days for 2 weeks). (B) Ovarian cancer volume was determined in mice administered WEB2086 and/or AG1478. The data represent the average (±SD). Student’s t-test was used to compare tumor sizes among the different treatment groups at day 21 following the start of treatment. ***, p < 0.001 indicates a statistically significant difference compared to the treatment with the single agent.

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