Figure 5

Time-course of AWT1 methylation after SCT. Evolution of AWT1 methylation and total WT1 expression in (A) patients who relapsed post-SCT (n = 5) and (B) patients in complete remission (n = 4). Black lines represent expression levels relative to the K562 cell line, with the dashed black lines representing the pathological thresholds for expression (0.55% of K562). The grey lines represent the methylation range observed in controls (14.6% ± 3 SD).