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Figure 3 | Journal of Hematology & Oncology

Figure 3

From: Developing aptamer probes for acute myelogenous leukemia detection and surface protein biomarker discovery

Figure 3

Comparison of aptamer recognition of AML leukemic cells and non-malignant CD34(+) cells. The AML cases were separated into three groups: 1) CD34(+) AML non-M3; 2) CD34(-) AML non-M3; and 3) AML M3. The fluorescence levels of bound aptamers or single-stranded negative control DNA were determined by flow cytometry. The fluorescence intensity levels of bound aptamers (folds over background) were calculated (a, JH6; b, JH19 and c, K19). Individual values for each aptamer bound on each case are shown as individual symbols, and mean ± standard deviation of individual groups are also shown. The P values are given as “*”, “**”, and “***” representing the P values of < 0.05, < 0.01, and < 0.001, respectively.

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