Figure 1

Proteasome subunit expression in bortezomib-resistant and bortezomib-sensitive 8226 (MM), THP1 (AML) and CEM (ALL) cells. Protein expression levels of constitutive proteasome subunits (β5, β1, and β2) and immunoproteasome subunits (β5i, β1i, and β2i) were determined by ProCISE and expressed in ng/μg total protein for 8226/WT, CEM/WT, THP1/WT, 8226/BTZ100, THP1/BTZ200 and CEM/BTZ200 cells. Percentages of individual subunits are given. Results depicted represent the mean (± SD) of 3 separate experiments.