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Figure 7 | Journal of Hematology & Oncology

Figure 7

From: Interferon-γ-induced upregulation of immunoproteasome subunit assembly overcomes bortezomib resistance in human hematological cell lines

Figure 7

PSMB8 (β5i) siRNA attenuates sensitizing effect of IFN-γ to bortezomib and ONX 0914. Cell growth inhibitory effects of (A) bortezomib and (B) ONX 0914 after PSMB8 or PSMB9 silencing in THP1/BTZ200 cells. Effects of PSMB8 and PSMB9 silencing on IFN-y sensitization of growth inhibition of THP1/BTZ200 cells to (C) bortezomib and (D) ONX 0914. Results depicted are the means (± SD) of 3 independent experiments.

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Journal of Hematology & Oncology

ISSN: 1756-8722

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