Figure 5From: Identification of a promising PI3K inhibitor for the treatment of multiple myeloma through the structural optimizationBENC-511 induces MM cell apoptosis. LP1, OCI-MY5, OPM2 and RPMI-8226 were treated with 1 μM of S14161, 0.5 or 1 μM of BENC-511 (BENC) and DMSO for 24 hours. Cells were then stained with Annexin V-FITC and PI and analyzed on a BD FACSCalibur™ flow cytometer.Back to article page