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Table 2 IMP3 signatures in cases and controls and IMP3 overexpression in serous tubal intraepithelial carcinoma and pelvic serous carcinoma

From: IMP3 signatures of fallopian tube: a risk for pelvic serous cancers

Group

#case

Mean

IMP3 signatures

STIC

PSC

  

age

(Total#)

#of + cases/HR (%)

#of + cases (%)

LR

196

48.6

25

0 (0)

0 (0)

HR

60

46.2

226

5/9 (55)

0 (0)

PSC

60

61.5

184

11/19 (58)

38 (63)

  1. HR: high-risk; STIC: serous tubal intraepithelial carcinoma; PSC: pelvic serous carcinoma. The frequency of IMP3 signatures was much higher in tubal fimbria of patients with high-risk (9.04-fold) and those with PSC (7.36-fold) than that in control group (p < 0.0001).