Figure 1From: Advances in understanding the cell types and approaches used for generating induced pluripotent stem cellsA proposed strategy for the tissue origins of iPSCs. Cells from three embryonic germ layers have been assessed through enormous research efforts, and the advantages that some tissue origins have over fibroblast origins concerning efficiency and accessibility have been elucidated. PBSs and HUCs are the most promising sources for iPSCs, but each of them has its own limitations. Further efforts are still needed to identify the ideal tissue for iPS generation that would be effective, safe, and convenient.Back to article page