CNV | |
---|
HGNC
|
Alteration
|
CN
| |
RET
| H.AMP | 4.4 | |
KRAS
| H.AMP | 4.2 | |
EGFR
| H.AMP | 4.7 | |
PTEN
| H.DEL | 0.9 | |
SNV
|
HGNC
|
Alteration
|
Consequence
|
Quality
|
AKT1
| c. G529A p. A117T | Likely benign | Low |
- Next generation sequencing of unusual responder patient with testicular cancer indicated tumor harboring multiple copy number aberrations. Only 5 alterations were found to have reported relevant information in tumors/cells treated with sunitinib: RET amplification, PTEN loss, EGFR and KRAS amplification.
- HGNC – Hugo genome nomenclature committee, CNV, copy number variation, SNV- Single nucleotide variants.
- NOTE: Genomic alterations detected may or may not have reported altered protein function.