Figure 1

YM155 suppresses survivin expression in a dose dependent manner in human ESCC cells. Eca109 and TE13 cells were treated with 1, 5, 10, 25, or 50 nmol/L YM155, or DMSO as control for 48 h. Protein expression levels of IAP family members were determined by Western blot analysis. GAPDH was used as loading control.