Figure 1From: Small-molecule survivin inhibitor YM155 enhances radiosensitization in esophageal squamous cell carcinoma by the abrogation of G2 checkpoint and suppression of homologous recombination repairYM155 suppresses survivin expression in a dose dependent manner in human ESCC cells. Eca109 and TE13 cells were treated with 1, 5, 10, 25, or 50Â nmol/L YM155, or DMSO as control for 48Â h. Protein expression levels of IAP family members were determined by Western blot analysis. GAPDH was used as loading control.Back to article page