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Figure 3 | Journal of Hematology & Oncology

Figure 3

From: Small-molecule survivin inhibitor YM155 enhances radiosensitization in esophageal squamous cell carcinoma by the abrogation of G2 checkpoint and suppression of homologous recombination repair

Figure 3

YM155 abrogates radiation-induced G 2 arrest in ESCC cells. A. Eca109 and TE13 cells were treated with YM155, X ray or the combination modality and then harvested for analysis of cell cycle distribution by flow cytometry. B. Cells treated with X ray alone or in combination with YM155 were then incubated in the absence (left panels) or the presence (right panels) of nocodazole (NOC, 0.4 μg/mL) for 24 h. Shown were representative flow cytometry plots of three experiments with similar results.

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