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Table 1 Radiosensitization effects of YM155 on ESCC cells in vitro

From: Small-molecule survivin inhibitor YM155 enhances radiosensitization in esophageal squamous cell carcinoma by the abrogation of G2 checkpoint and suppression of homologous recombination repair

  D0(Mean inactivation dose) Dq Surviving fraction (2 Gy) Sensitization enhancement ratio
Eca109  
Control 2.74 1.78 0.72  
YM155 (5 nM) 2.34 0.13 0.44 1.20
YM155 (10 nM) 1.82 0.03 0.34 1.51
TE13  
Control 1.52 1.97 0.71  
YM155 (5 nM) 0.98 1.41 0.44 1.55
YM155 (10 nM) 0.88 0.82 0.24 1.73