Table 2 Abrogation of G2/M checkpoint by YM155 in ESCC cells
| Â | Eca109 | TE13 | ||||
|---|---|---|---|---|---|---|
Treatment | G1(%) | S (%) | G2/M (%) | G1(%) | S (%) | G2/M (%) |
Control | 42.7 | 26.3 | 28.0 | 45.7 | 27.4 | 23.9 |
YM155 | 51.4 | 22.2 | 22.6 | 59.6 | 35 | 7.8 |
IR | 13.6 | 23.1 | 62.5 | 23.4 | 8.7 | 66.8 |
IR + YM155 | 45.8 | 14.3 | 34.7 | 46.6 | 13.2 | 36.4 |
Treatment | G 1 (%) | S (%) | G 2 /M (%) | G 1 (%) | S (%) | G 2 /M (%) |
Control | 42.1 | 43.3 | 13.9 | 39.7 | 39.9 | 18.7 |
IR | 12.4 | 25.1 | 60.0 | 32.9 | 21.4 | 46.0 |
IR + Noc | 2.6 | 10.8 | 84.5 | 5.4 | 18.8 | 73.0 |
IR + YM155 | 36.8 | 31.2 | 28.9 | 43.5 | 18.2 | 35.9 |
IR + YM155 + Noc | 20.7 | 36.0 | 41.4 | 32.1 | 11.2 | 55.9 |