Skip to main content

Table 2 Univariate and multivariate Cox regression analyses FENDRR for DFS or OS of patients in study cohort (n = 158)

From: Decreased expression of the long non-coding RNA FENDRR is associated with poor prognosis in gastric cancer and FENDRR regulates gastric cancer cell metastasis by affecting fibronectin1 expression

Variables DFS OS
  HR 95% CI p value HR 95% CI p value
Univariate analysis       
Age (<50 years vs. >50 years) 0.935 0.618-1.415 0.752 0.954 0.599-1.520 0.843
Gender (male vs. female) 0.805 0.525-1.233 0.318 0.771 0.475-1.252 0.293
Location (Distal vs. Middle + Proximal) 0.827 0.546-1.254 0.372 0.714 0.448-1.138 0.157
Tumor size ( >5 cm vs. <5 cm ) 1.392 0.917-2.113 0.120 1.236 0.975-1.565 0.079
Histologic differentiation(Well + Moderately vs. Poorly + Undifferentiated) 1.264 0.826-1.933 0.281 1.518 0.932-2.474 0.094
Invasion depth (T1 + T2 vs.T3 + T4) 1.306 0.863-1.978 0.207 1.323 0.829-2.111 0.240
TNM stage (I + II vs. III + IV) 0.470 0.308-0.717 <0.001* 0.405 0.251-0.653 <0.001*
Lymphatic metastasis (No vs. Yes) 0.617 0.404-0.924 0.025* 0.624 0.389-1.000 0.05*
Regional lymph nodes (PN2+ PN3 vs. PN0+ PN1) 0.626 0.410-0.954 0.029* 0.570 0.356-0.912 0.019*
Distant metastasis (No vs. Yes) 0.493 0.279-0.874 0.015* 0.523 0.275-0.996 0.049*
Expression of FENDRR (High vs. Low) 0.563 0.370-0.856 0.007* 0.539 0.337-0.862 0.010*
Multivariate analysis       
TNM stage (I + II vs. III + IV) 0.566 0.333-0.962 0.035* 0.458 0.253-0.828 0.010*
Lymphatic metastasis (No vs. Yes) 0.740 0.408-1.342 0.322 0.913 0.458-1.822 0.797
Regional lymph nodes (PN0+ PN1vs. PN2+ PN3) 0.658 0.338-1.283 0.220 0.779 0.363-1.674 0.522
Distant metastasis (No vs. Yes) 0.577 0.298-1.117 0.103 0.672 0.320-1.411 0.294
Expression of FENDRR (High vs. Low) 0.555 0.344-0.897 0.016* 0.569 0.321-0.960 0.042*
  1. *Overall p < 0.05.