Figure 6
From: Highly efficient, In-vivo Fas-mediated Apoptosis of B-cell Lymphoma by Hexameric CTLA4-FasL
CTLA4-FasL inhibits tumor growth in vivo . Ex vivo JY cells were injected subcutaneously to irradiated NUDE mice. At day 5 after JY injection, tumor volume was calculated and mice were treated daily with subcutaneous injections of CTLA4-FasL or PBS for 5 days. (A) Tumor volume. Results represent the mean +/- SE volume of tumors, (n = 10 for each group). *P < 0.05 between PBS group and 10 ug*2 or PBS vs 25 ug*2. **P <0.01 respectively. (B) The survival curve of the experimental groups and control.