|
Variables
|
Low (<150) N = 67
|
Low normal (150-229) N = 361
|
Mid-normal (230-314) N = 379
|
High normal (315-399) N = 169
|
HIGH (≥400) N = 75
|
|---|
|
Number dead (%)
|
37 (55)
|
150 (42)
|
146 (39)
|
105 (62)
|
53 (71)
|
|
Median Survival Months (95% CI)
|
37.7 (20.7- 84.8)
|
64.0 (53.6-78.9)
|
74.7 (60.7 100.4)
|
23.8 (17.7 - 36.7)
|
16.3 (11.8 -29.2)
|
|
p-value for difference
| | | | |
<0.0001
|
|
Overall Survival
| | | | | |
|
Unadjusted HR (95% CI)
|
1.52 (1.06-2.18)
|
1.07 (0.85-1.34)
|
1.0 (reference)
|
1.98 (1.54-2.55)
|
2.64 (1.92 -3.61)
|
|
Adjusted HR (95% CI)
|
1.50 (0.96-2.35)
|
1.25 (0.93-1.68)
|
1.0 (reference)
|
2.20 (1.58-3.05)
|
2.37 (1.60-3.50)
|
|
HR (95% CI) by Stage
| | | | | |
|
I (n = 103)
|
0.41 (0.05-.3.31)
|
1.18 (0.33-4.20)
|
1.0 (reference)
|
1.60 (0.27-9.54)
|
0.35 (0.03-4.18)
|
|
II (n = 95)
|
1.99 (0.52-7.67)
|
1.40 (0.57-3.38)
|
1.0 (reference)
|
1.54 (0.48-4.99)
|
1.83 (0.45-7.40)
|
|
III (n = 146)
|
0.74 (0.16-3.40)
|
1.32 (0.62-2.82)
|
1.0 (reference)
|
2.43 (0.91-6.50)
|
1.86 (0.53-6.45)
|
|
IV (n = 478)
|
2.33 (1.34-4.10)
|
1.18 (0.78-1.78)
|
1.0 (reference)
|
2.50 (1.66-3.76)
|
2.47 (1.55-2.93)
|
- Adjusted model controls for age, race, site, grade, treatment, smoking and stage.
- P for interaction between stage and classes of platelets p = 0.31.
