Figure 2
From: Strategies for modern biomarker and drug development in oncology
Molecular pathways in cancer progression. This figure identifies some of the common pathways involved in cancer cell growth and proliferation. Proteins such as Receptor Tyrosine Kinases (RTKs) (i.e. EGFR, HER2, VEGFR, PDGFR, IGFR, KIT) PI3K, AKT, RAF, MEK, and SHH represent some of the drug targets in precision medicine.