Circulating miRNAs in cancer: from detection to therapy

Table 1 Summary of the circulating miRNAs that may be used as non-invasive biomarkers for the detection of cancer

Circulating miRNA	Types of cancer	Methods	Source	References
miR-155,-210,-21	Diffuse large B-cell lymphoma	qRT-PCR	serum	[14]
miR-132, -181c, -15a, -370, -143-3p, -21-5p, -200a-3p, -646	Cervical squamous cell carcinoma	TaqMan miRNA array, qRT-PCR	serum	[26]
miR-122	Chronic hepatitis B	Microarray, qRT-PCR	serum	[28]
miR-141	Prostate cancer	qRT-PCR	serum/plasma	[29],[41]
miR-1233	Renal cell carcinoma	TaqMan low density array, qRT-PCR	serum	[30]
mir-16,-25	Multiple myeloma	NanoString-nCounter microRNA assays	serum	[31],[52]
miR-17, -20a, -29c, -223	Nasopharyngeal carcinoma	Microarray, qRT-PCR	serum	[32]
miR-17-3p, -29a, -92a, -221	Colorectal Cancer	qRT-PCR	serum	[41],[42],[51]
miR-155	Breast Cancer	TaqMan miRNA array, qRT-PCR	serum	[41],[49],[54]
miR-21, -26a, -27a, -122, -192, -223, -801	Hepatocellular cancer	Microarray, qRT-PCR	serum	[48]
miR-16, -25, -92a, -451, miR-486-5p	Gastric non-cardia adenocarcinoma	TaqMan low density array, qRT-PCR	serum	[50]
miR-425-5p, -93-5p	Head and neck cancer	qRT-PCR	Plasma	[53]
miR-122	Chronic hepatitis C	qRT-PCR	serum	[55]

ISSN: 1756-8722