Figure 1

c-FLIP was overexpressed and related to decreased TRAIL/DR5 expression in PTCLs patients. Long and short isoform of c-FLIP gene (c-FLIP _L and c-FLIP _S ) (A), as well as TRAIL and DR5 expression (B) were detected by real-time PCR in PTCLs, T-ALL and reactive hyperplasia. ***, P < 0.001 comparing with reactive hyperplasia. All gene expression levels were calculated by ^ΔΔCT method based on the calibrator Jurkat cells.