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Table 1 Summary of miRNA expression signatures as prognostic parameters

From: Microrna expression signatures predict patient progression and disease outcome in pediatric embryonal central nervous system neoplasms

MicroRNAs Disease progression high → low Clinical outcome MiRNA property (Initial analysis) MiRNA property (Meta-analysis) Prognosis
High → low
miR-3681 CR/R/C A/D/C Oncogene Oncogene Inferior
miR-601 CR/R/C A/D/C Oncogene Tumor-suppressor gene Favorable
miR-320e R/CR/C D/A/C Oncogene Tumor-suppressor gene Favorable
miR-34a R/CR/C N/A Oncogene Oncogene Inferior
miR-642a CR/R/C A/D/C Oncogene Tumor-suppressor gene Favorable
miR-720 C/CR/R C/A/D Tumor-suppressor gene Tumor-suppressor gene Favorable
miR-891a C/R/CR C/D/A Tumor-suppressor gene Tumor-suppressor gene Favorable
miR-522 C/R/CR N/A Tumor-suppressor gene Oncogene Inferior
miR-518c C/CR/R N/A Tumor-suppressor gene Oncogene Inferior
miR-3665 C/CR/R N/A Tumor-suppressor gene Tumor-suppressor gene Favorable
miR-3620 C/CR/R N/A Tumor-suppressor gene Tumor-suppressor gene Favorable
miR-382 C/CR/R N/A Tumor-suppressor gene Tumor-suppressor gene Favorable
miR-452 C/CR/R N/A Tumor-suppressor gene Tumor-suppressor gene Favorable
miR-136 R/CR/C A/D/C Oncogene Oncogene Inferior
miR-26b CR/R/C A/D/C Oncogene Oncogene Inferior
miR-122 C/CR/R N/A Tumor-suppressor gene Tumor-suppressor gene Favorable
miR-147 C/CR/R N/A Tumor-suppressor gene Oncogene Inferior
miR-192 R/CR/C N/A Oncogene Oncogene Inferior
  1. High → Low expression, CR; clinical remission, R; relapse, C; control, A; alive, D; deceased, P; positive, N/A; not applicable.