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Figure 1 | Journal of Hematology & Oncology

Figure 1

From: Evaluation of the anti-tumor effects of lactate dehydrogenase inhibitor galloflavin in endometrial cancer cells

Figure 1

Galloflavin inhibited cell proliferation in the ECC-1 and Ishikawa cells. The ECC-1 and Ishikawa cell lines were cultured in 96-well plates for 24 hours and treated with GF at the indicated doses for 72 hours. Cell proliferation was assessed with MTT assay (A). The cells were cultured in 6 well plates for 24 hours, treated with GF for 48 hours and then cultured for an additional 10 days. Colony formation assay was assessed (B, C). The effect of GF on LDHA activity level was examined using a LDHA activity assay kit (D). GF decreased LDHA activity in the endometrial cancer cells after 16 hours of treatment. (* < 0.05).

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