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Figure 2 | Journal of Hematology & Oncology

Figure 2

From: Galectin-3 mediates bone marrow microenvironment-induced drug resistance in acute leukemia cells via Wnt/β-catenin signaling pathway

Figure 2

Gal-3 is necessary for drug resistance of ALCs induced by hBM-MSCs. (A) ALCs (Reh, Jurkat and Kasumi-1 cells) were transfected by gal-3 shRNA or vector as control. Western blot and real time PCR analysis of gal-3 in transfected ALCs under different conditions, namely cultured alone or with hBM-MSCs. (B) The apoptotic levels of transfected ALCs without any cytotoxic drugs. (C) The apoptotic levels of transfected ALCs treated with IDA at the concentrations described above. Vc: cells transfected with vector; Gal-3i: cells transfected with gal-3 shRNA.

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