Skip to main content
Figure 1 | Journal of Hematology & Oncology

Figure 1

From: High expression of neuroguidin increases the sensitivity of acute myeloid leukemia cells to chemotherapeutic drugs

Figure 1

Proliferation inhibition and apoptosis in NGDN over-expressing leukemia cells (K562/A02-NGDN) after chemotherapeutic drugs treatment. The level of proliferation inhibition was examined using the CCK-8 assay following treatment with different concentrations of chemotherapeutic drugs for different lengths of time. The percentages of proliferation inhibition in K562/A02-NGDN and control K562/A02 cells after treatment with (A) vincristine (VCR), (B) etoposide (VP-16) and (C) epirubicin (EPI) are shown (mean ± SD, n = 3, star symbols: P < 0.05). The level of apoptosis was assessed using annexin V-FITC/allophycocyanin (APC ) staining by flow cytometry. The percentages of apoptosis in K562/A02-NGDN and control K562/A02 cells after treatment with (D) VCR, (E) VP-16, and (F) EPI are shown (mean ± SD, n = 3, star symbols: P < 0.05). NGDN: neuroguidin.

Back to article page

Journal of Hematology & Oncology

ISSN: 1756-8722

Contact us