Figure 3
Comparison of the stability of fusion proteins antiCD3Fv-⊿IL3 and ds-antiCD3Fv-⊿IL3 in vitro . The stability was determined by testing binding activity of fusion proteins to (A) CD3-positive Jurkat cells or (B) CD123-positive KG1a cells after incubation in 0.2% HSA at 37°C for a prolonged time period. Data were normalized to t 0 (initial time), which was set at 100%. The data shown represent the averages of three independent experiments.