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Figure 2 | Journal of Hematology & Oncology

Figure 2

From: Soluble NKG2D ligand promotes MDSC expansion and skews macrophage to the alternatively activated phenotype

Figure 2

Injection of sMICB promotes accumulation of MDSC and Arginase I+ macrophage in the peritoneal. (a) Representative flow cytometry plots and summary data demonstrating the percentage of CD11b+Gr-1+ population in peritoneal exudate cells (PECs) harvested from B6 (n = 6) or BALB/c (n = 5) mice 3 days post i.p. injection with 200 μg sMICB. (b) Representative flow cytometry plots and summary data demonstrating expression of macrophage subtype marker CD206 (type II) and CD11c (type I) on gated F4/80+ PECs 6 days post sMICB injection. (c) Representative flow cytometry plots and summary data demonstrating arginase I expression in F4/80+CD206+ PECs. Data represent four independent experiments. *P < 0.05. **P < 0.01.

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