Figure 5
SUMO2-C/ebpa, POZ-C/ebpa rescue assay in dnmt1 morphants and ldd794 dnmt1 mutants. (A-H) SUMO2-C/ebpa and POZ-C/ebpa restored cmyb expression in dnmt1 MO knockdown morphants at 36 hpf (A-D) and 5 dpf (E-H). (I-N) SUMO2-C/ebpa mRNA restored cmyb expression in the AGM region at 36 hpf (K) and the CHT region at 3 dpf (N) of ldd794 dnmt1 mutants. (A’-N’) Magnified images of the boxed regions in A to N. Red arrows indicate cmyb-positive HSPCs in the AGM or CHT.