Figure 2

Prognostic value of RIP140 in CLL patients. (A) Patients of the Herold’s cohort (n = 107) were ranked according to increasing RIP140 expression and a maximum difference in OS was obtained with an expression cutoff of 7.49 using the Maxstat R function. (B) Low RIP140 expression is associated with a shorter time to the first treatment in CLL patients. The data were normalized using the robust multichip average (RMA) method and Affymetrix gene expression data are publicly available via the online Gene Expression Omnibus (http://www.ncbi.nlm.nih.gov/geo/) under accession number GSE22762, and GSE25571.