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Table 1 The expression level of VSTM1 in bone marrow cells from leukemia patients and healthy donors

From: VSTM-v1, a potential myeloid differentiation antigen that is downregulated in bone marrow cells from myeloid leukemia patients

Groups

MIC

Sample size

Mean ratio, VSTM1 / ABL

P value a

HD

 

36

17.358 ± 17.904

 

Untreated AML

 

145

4.333 ± 7.895

<0.001

 

M1

3

0.374 ± 0.619

n.a.

 

M2

72

5.292 ± 10.171

<0.001

 

M3

29

2.884 ± 3.960

<0.001

 

M4

24

4.814 ± 5.293

0.001

 

M5

14

3.052 ± 4.867

<0.001

 

M6

3

1.417 ± 2.205

n.a.

Untreated ALL

 

40

0.381 ± 0.755

<0.001

Untreated CML

 

57

5.479 ± 8.266

<0.001

 

CP

38

7.743 ± 9.312

0.001

 

AP/BC

19

0.950 ± 1.367

<0.001

  1. MIC morphological, immunological, and cytogenetic classifications, n.a. not available due to a small sample size.
  2. aThe P value was calculated using Wilcoxon signed ranks test as compared to the HD group.